Johns Hopkins – Technologies to address

Self-spreading vaccines—also known as transmissible or self-propagating vaccines—are genetically engineered to move through populations in the same way as communicable diseases, but rather than causing disease, they confer protection. The vision is that a small number of individuals in the target population could be vaccinated, and the vaccine strain would then circulate in the population much like a pathogenic virus. These vaccines could dramatically increase vaccine coverage in human or animal populations without requiring each individual to be inoculated. This technology is currently aimed primarily at animal populations. Because most infectious diseases are zoonotic,40 controlling disease in animal populations would also reduce the risk to humans.”

Click to access 181009-gcbr-tech-report.pdf